Lesson Plan: ADH (Antidiuretic Hormone)

Subject: Biology Level: A-Level

Prior Knowledge Introduction: - Begin the lesson by asking students to recall their knowledge of the human excretory system and the role of the kidneys in maintaining homeostasis. - Review the concept of osmoregulation and the importance of maintaining water balance in the body. - Ask students if they have heard of ADH (Antidiuretic Hormone) and if they know its role in the body.

Lesson Outline: 1. Introduction to ADH (10 minutes) a. Define ADH and explain its role in regulating water balance in the body. b. Discuss the location of ADH production (hypothalamus) and its release from the posterior pituitary gland. c. Highlight the importance of ADH in preventing excessive water loss through urine.

1. Mechanism of ADH Action (15 minutes) a. Explain the mechanism of ADH action on the kidneys, specifically the distal convoluted tubules and collecting ducts. b. Discuss how ADH increases the permeability of these tubules to water, leading to water reabsorption and concentrated urine formation. c. Use diagrams or animations to illustrate the process.

2. Regulation of ADH Release (15 minutes) a. Introduce the concept of negative feedback and its role in regulating ADH release. b. Discuss the factors that stimulate or inhibit ADH release, such as changes in blood osmolarity and blood pressure. c. Explain the role of the hypothalamus and osmoreceptors in detecting changes in blood osmolarity.

3. Higher Order Questioning (10 minutes)

   • Engage students in higher-order thinking by asking the following questions: a. How does ADH help in maintaining water balance in the body? b. What would happen if ADH secretion is impaired? c. Can you think of any diseases or conditions related to ADH dysfunction?

Assessment: - Distribute a worksheet to students to assess their understanding of ADH and its role in water balance regulation. - The worksheet should include multiple-choice questions, short answer questions, and a diagram labeling activity.

Differentiation: - Provide additional resources, such as articles or research papers, for students who want to explore the topic further. - Offer support to students who may require extra assistance by providing simplified explanations or additional examples.

Plenary: - Summarize the key points covered in the lesson, emphasizing the role of ADH in maintaining water balance. - Ask students to reflect on the importance of ADH in the overall functioning of the excretory system. - Encourage students to ask any remaining questions or seek clarification on any concepts they found challenging.

Video Resources: 1. Khan Academy: ADH and Osmoregulation - https://www.khanacademy.org/science/biology/human-biology/water-electrolysis/v/antidiuretic-hormone-adh-and-osmoregulation 2. Amoeba Sisters: ADH and Osmoregulation - https://www.youtube.com/watch?v=3vX0Zs5g3Ww

Worksheet Resources: 1. ADH Worksheet - https://www.biologycorner.com/worksheets/adh.html 2. ADH and Osmoregulation Worksheet - https://www.teacherspayteachers.com/Product/ADH-and-Osmoregulation-Worksheet-3840517